Review Of The Most Commonly Abused Drug In The United States Is Ideas. Web the most commonly used illicit drug was marijuana, which 52.5 million people used. 9.2 million people 12 and older misused opioids in the past year.

Web in 2022, 70.3 million people aged 12 or older (or 24.9%) used illicit drugs in the past year. Results from the 2020 national survey on drug use and health. In 2022, 48.7 million people aged 12 or older (or 17.3%) had a substance use disorder (sud) in the past year, including.